Uterine transplantation is a chance for women with organic infertility to bear and give birth to a child.
Reproductive medicine has made great progress in recent decades, especially with the introduction of in vitro fertilization in the late 1970s and intracytoplasmic sperm injections in the early 1990s. However, in case of absolute uterine infertility (which is approximately one case per 500 women) due to the absence of uterus or violation of organ functions, the only solution was surrogate motherhood.
Uterine transplantation is an opportunity to restore a lost organ or its functions, and then to bear and give birth to a child on its own. The first transplant was registered in 2002, and the second one in 2011, as it took time to improve the method. A little later, a whole series of transplants was performed in Sweden in 2012-13 - 9 operations. Seven of them proved to be perfectly viable, and after the hormonal therapy cycle, women had a regular menstrual cycle for several years.
To date, 11 uterine transplants have been performed worldwide, and this method is actively being prepared for clinical implementation. Currently, the main work is being done to prevent organ rejection, but not to use drugs that are dangerous for the fetus during pregnancy, as most drugs penetrate the placental barrier and can cause complications and malformations.
There are already cases of healthy babies in women who have had a uterine transplant. In this case, organ rejection and other complications have been avoided.
Such advances in medicine show that doctors can become magicians for their patients, even if the situation seems hopeless.